Problem Set 6 Problems On Gene Expression Repair And Protein Synthesis Degrada

Problem Set 6 – Problems on Gene Expression/Repair and Protein Synthesis/Degradation (3problems):

16. The DNA in a human non-gametic cell contains 6 billion base pairs. It is estimated thatabout 10,000 DNA changes occur in each cell in one day. These are quickly repaired so thatonly a few (1 to 5) mutations accumulate in one cell in a year.

a. What percentage of the base pairs are altered each day?

b. What percentage of the DNA changes that occur in one cell in one year escapethe proofreading and repair process – calculate this in both cases: if 1 mutationaccumulates in one cell per year, and if 5 mutations accumulate in one cell peryear?

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