Local Anaesthetic Agents A Are Primarily K Channel Blockers B Prevent Repolarisa

Local anaesthetic agents

 a. Are primarily K+ channel blockers

 b. Prevent repolarisation of the membrane

 c. Can be used with a vasodilator to prolong local action

 d. Activity is enhanced by high extracellular K+ concentration

 e. Activity is enhanced by high extracellular Ca2+

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